April 12: Comprehensive Wiring and Assembly instructions for the control box are posted on the Downloads page.
April 9-12: Fabrication commences on 100 units.
April 8: 4-hour live swine study was a success, with no complications or adverse events. Inspiratory pressure, end-tidal CO2 levels, and blood-gas levels were all clinically acceptable throughout. Currently awaiting histology results.
April 7: Breathing-assist tested, and second animal study scheduled for the morning of April 8th to test long-term ventilation.
April 5: Alarms and mechanical safety features integrated.
April 4: Breathing-assist functionality integrated.
April 3: First live animal study on a porcine model with CoV v3.1 was a success.
April 2: Nissan donates 100 wiper motors. Make Nashville joins the team as a fabrication facility.
April 1: IACUC protocol approved. First animal study scheduled.
March 30-April 1: Substantial how-to content loaded onto VandyVents.com. Parts to be able to build 100 units arrive.
March 30: IACUC Protocol submitted for first animal test. Second copy of V3 design fabricated. Long-term running tests initiated. Ongoing discussions regarding clinical considerations.
March 29: Motor control and electronic pressure sensing integrated into V3 prototype. VandyVents web page goes live; thanks to Dominick Ropella for setting it up. George P. Johnson, Inc. volunteers to assist with fabricating plywood pieces. FDA approval efforts initiated.
March 28: V3 prototype incorporating Nissan motors is completed.
March 26: Nissan donates 5 initial windshield wiper motors from the Nissan Altima.
March 25: First ex vivo test in a pig lung and with a respiratory training mannequin in CELA at Vanderbilt.
March 24: Manometer-based sensor with light-based over and under-pressure sensors implemented. Arduino-based closed-loop control implemented.
March 23: V2 prototype assembled. First Zoom team meeting with physicians Fabien Maldonado and Matthew Bacchetta. Arna Banerjee, Craig Rooks, Erin Gillaspie subsequently join the team.
March 22: First prototype assembled. Postdoc Josh Gafford, and PhD students Max Emerson and Katy Riojas quickly volunteer to join the team.
March 21: The VandyVents project begins. Duke Herrell calls Bob Webster and expresses urgent need to get working on a ventilator. Eric Barth tells Bob that Kevin Galloway has a great napkin-sketch ventilator design. Our team begins to come together.